Integration of AI Approaches in Preclinical Academic Settings to Target a Challenging Solute Carrier (SLC) Target

• Combine patient-derived, multi-omic data with AI modeling to enable the discovery of underexplored transporter targets linked to neurological disease
• Identify new chemical probes that modulate transporter activity using structure-based virtual screening, molecular modeling, and rational design
• Share how integrative computational and experimental workflows provide a roadmap for expanding the druggable target landscape beyond enzymes and receptors

Speakers:

Avner Schlessinger

Professor & Director - Pharmacology & Therapeutics Discovery Training Area

AI Small Molecule Drug Discovery Center, Icahn School of Medicine at Mount Sinai